Preheat the oven to 350°F: Line or grease a standard 12-cup muffin tin and set aside.
Cream the butter and sugar: In a large mixing bowl, beat the softened butter and brown sugar together until light and fluffy.
Add the wet ingredients: Beat in the egg, then stir in the sour milk and vanilla extract until everything is well combined.
Mix the dry ingredients: In a separate bowl, whisk together the flour, baking soda, baking powder, and salt.
Combine the wet and dry: Add the dry ingredients to the wet mixture and stir gently until just combined. Be careful not to overmix.
Fold in the rhubarb: Gently fold in 1½ cups of chopped rhubarb until evenly distributed.
Scoop the batter into the muffin tin: Fill each muffin cup about ¾ full with batter.
Make the cinnamon crumble topping: In a small bowl, mix together the brown sugar, flour, and cinnamon. Cut in the cold, cubed butter using your fingers or a pastry cutter until the mixture resembles coarse crumbs.
Top the muffins: Sprinkle the crumble evenly over each muffin, then add a few extra pieces of chopped rhubarb to the tops.
Bake until golden and set: Place in the oven and bake for 22–25 minutes, or until a toothpick inserted into the center comes out clean.
Cool before serving: Let the muffins cool in the pan for 5 minutes before transferring to a wire rack to cool completely.